Oxycodone Dosage Guide for Adults

This page is for educational reference only. It is not a substitute for personalized medical advice. Always follow the dose prescribed for you.

Immediate-release oxycodone (30 mg tablets)

• Typical adult dose: 30 mg every 4–6 hours as needed.
• Maximum: typically not more than 240 mg in 24 hours.
• With or without food: may be taken with food to reduce nausea.

Modified-release oxycodone

• Strengths: 60 mg, 90 mg, 120 mg.
• Typical schedule: one tablet every 12 hours.
• Do not crush or chew: doing so releases the full dose at once and can be dangerous.

Starting dose & titration

Most prescribers start at the lowest effective dose and titrate upward only if pain control is inadequate. Sudden increases significantly raise the risk of side effects, especially respiratory depression and sedation.

Special populations

• Older adults: often require lower doses due to increased sensitivity and reduced clearance.
• Kidney/liver impairment: dose adjustments are typically required — discuss with your clinician.
• Pregnancy/breastfeeding: oxycodone is generally avoided unless benefits clearly outweigh risks.

Missed dose

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double up.

Stopping oxycodone

If you have taken oxycodone for more than a few weeks, do not stop abruptly. Tapering under medical supervision reduces the risk of withdrawal symptoms.